This is it, football fan! The final week of the 2025-26 NFL regular season has arrived. Two games will take place on Saturday, another 14 will be played on Sunday, and that two-day stretch will put the finishing touches on this year's playoff field.

Welcome to the Monday edition of the Pick Six newsletter! This is it. This is your final newsletter of 2025 and we're going to go out with a bang, which is the opposite of what Pittsburgh did on Sunday.

The NFL’s final weekend of the regular season features a winner-take-all game between the Ravens-Steelers and a battle for the NFC’s No. 1 seed between the Seahawks-49ers. There’s also the Panthers-Buccaneers matchup that will decide the NFC South,

The 49ers will play the Seahawks for the No. 1 seed next weekend at Levi’s Stadium, with the winner getting the coveted first-round bye. But, after the Los Angeles Rams had a surprise 27-24 loss to the Atlanta Falcons, there are a few more scenarios for how the NFC playoff seeding could end up.

With the final week of the regular season upon us, three teams from the NFC West are in the top five in the odds to win the Super Bowl. The Los Angeles Rams, the favorites for the last several weeks,