Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales. Oral tebipenem pivoxil hydrobromide (HBr), a carbapenem, is as effective as ...

IDSA recommends shorter antibiotic courses for adults with cUTIs who show clinical improvement on effective therapy.

Background and aims: Urinary tract infections (UTIs) are relatively common infections in children. Findings on nuclear renal scans suggest that the vast majority of infants and young children with ...

Cefepime-taniborbactam, an investigational beta-lactam and beta-lactamase inhibitor combination, was superior to meropenem for the treatment of hospitalized patients with complicated urinary tract ...

Please provide your email address to receive an email when new articles are posted on . Cefepime-enmetazobactam demonstrated superiority compared with piperacillin-tazobactam in a phase 3 trial ...

intravenous antibiotics Cefepime-enmetazobactam may be more effective than piperacillin-tazobactam in treating complicated UTI and acute pyelonephritis caused by organisms that produce ...

"The five factors with the highest odds of developing APN included obstructive and reflux uropathy, presentation to an acute care facility, urinary retention, history of UTI, and renal comorbidities.

Carbapenem-resistant Enterobacterales and multidrug-resistant Pseudomonas aeruginosa are a global threat to antimicrobial resistance and may be causative pathogens in cUTI. Cefepime-taniborbactam ...

A young male cadaveric kidney transplant developed delayed graft function. In addition to fever, serial allograft biopsies revealed progressive infiltration of polymorphonuclear leukocytes. After ...

Credit: Getty Images. The application submission is supported by data from the phase 3 ADAPT-PO trial, which compared oral tebipenem HBr to ertapenem in adults with cUTI or acute pyelonephritis. A New ...

GlaxoSmithKline (GSK) has resubmitted a new drug application (NDA) to the US Food and Drug Administration seeking approval of tebipenem pivoxil hydrobromide (HBr), an investigational oral carbapenem ...