Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't ...

A collaborative effort by the Formosa-Jordan lab from the Max Planck Institute for Plant Breeding Research in Cologne, Germany, the Fox lab from Duke University, U.S., and the Roeder lab from Cornell ...

Assistant Professor of Biomedical Engineering Yi Xue works on 2P-FOCUS, a new two-photon microscopy system, in her lab. The system promises novel insights into biological features that were once only ...

Researchers developed a way to 'de-crowd' molecules in a cell by expanding a tissue sample, labeling the molecules, then imaging them. The method, known as expansion revealing, builds on a technique ...

What is Scanning Ion Conductance Microscopy? Scanning Ion Conductance Microscopy (SICM) is a non-contact scanning probe microscopy technique that enables high-resolution imaging of living cells and ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

Researchers developed a large-scale, dynamic imaging technique using mesoscopic oblique plane microscopy, which can capture 3D images of entire organisms and maintain cellular resolution. A new ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

TEMI mapping of lipid distribution across cerebellar layers. This image shows lipid species specifically enriched in three distinctive layers of the cerebellum: molecular layer, white matter layer and ...

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...