Eleven patients with refractory autoimmune hemolytic anemia (AIHA) were all brought into drug-free remission with CAR T-cell ...
China: CAR T-cell therapy, already in use for certain B-cell–driven autoimmune diseases such as lupus, has now demonstrated ...
Scientists from the Institute of Molecular Genetics of the Czech Academy of Sciences, in collaboration with the Faculty of ...
Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...
For starters, she pointed out that standard CAR-T therapy involves a lymphodepletion regimen with cyclophosphamide and ...
Autoimmune diseases share the same core pathology despite their differing clinical manifestations: dysregulated B and T cell activity. B cells contribute to disease progression by secreting ...
In a discussion hosted by Dr. Zachary Roberts, Executive Vice President of R&D and Chief Medical Officer at Allogene Therapeutics, leading rheumatologists Dr. Chris Wincup of King’s College Hospital ...
Cue Biopharma, Inc. has announced that it has received positive Pre-Investigational New Drug (Pre-IND) feedback from the FDA regarding its planned first-in-human trial for CUE-401, a novel bispecific ...