Methamphetamine doesn't just spike levels of the pleasure-inducing hormone dopamine in the reward pathways of the brain—it ...

Monkey experiments hint at a "motivation brake" pathway between two brain regions. Manipulating it may lead to new treatments ...

Methamphetamine addiction has long been framed as a story of dopamine gone haywire, with the drug flooding the brain’s reward ...

Scientists have uncovered a way to manipulate the pathway in monkey brains that puts the brakes on motivation.

There is also a warning embedded in the findings: a brake exists for a reason. If it is weakened too much, a person might push into highly stressful situations too readily, which could increase risk ...

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing ...

(CNN) — Maybe you’d like to spend time on hobbies or hang out with friends, but nothing feels as exciting and engaging as it used to –– so you just squander another hour on social media. Your problem ...

LOS ANGELES — Maybe you'd like to spend time on hobbies or hang out with friends, but nothing feels as exciting and engaging as it used to –– so you just squander another hour on social media. Your ...

You know exercise is good for you, but your brain still resists it like it’s punishment rather than reward. The problem isn’t willpower or discipline – it’s that your neural pathways haven’t learned ...