Cholesterol plays an indispensable role in embryonic development, cell membrane integrity and the biosynthesis of steroid hormones. Disorders of cholesterol biosynthesis disrupt these vital processes, ...

The raw material for de novo fatty acid synthesis is acetyl-CoA, which can be obtained via the citrate shuttle pathway or from acetic acid. ACC and FASN catalyze the conversion of acetyl-CoA into ...

Researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice. Like all cancers, bladder ...

Traditional Chinese medicine offers promising natural compounds that modulate cholesterol metabolism, unveiling new therapeutic pathways for cancer treatment. Study: Targeting cholesterol metabolism: ...

Cholesterol-lowering medicines are some of the most commonly prescribed, effective drugs. But to influencers on TikTok, they're the enemy. The cholesterol-lowering drug Simvastatin. Like other statins ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this journey through a disease state contains ...