Dupuytren's contracture, also known as Dupuytren's disease, occurs with a thickening of the tissue fibers in the layer below the palm and skin of the fingers. The condition often does not cause pain, ...

Dupuytren’s disease (also known as Dupuytren’s contracture) is a benign condition of the skin characterized by the overgrowth of myofibroblasts. The reasons for this type of proliferation are unknown ...

Xiaflex (collagenase clostridium histolyticum) is a brand-name injection that’s prescribed for Peyronie’s disease and Dupuytren’s contracture in adults. As with other drugs, Xiaflex can cause side ...

Arthrogryposis is when a baby has one or more permanently-extended joints, known as contracture, at birth. Arthrogryposis is often manageable and does not typically affect life expectancy. A ...

We thank Drs Patrick, Farmer and Bromwich for their interest in our paper. In their letter they raised four main issues: contracture is not solely due to the loss of sarcomeres in muscles but also due ...

In mice, the drug bortezomib preserved muscle growth and prevented loss of elbow and shoulder motion in conditions resembling cerebral palsy and newborn brachial plexus injury, the most common causes ...