A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

Extending their collaboration, Genialis and Debiopharm continue working towards a patient classifier to support WEE1 clinical development BOSTON--(BUSINESS WIRE)-- Genialis, the RNA biomarker company, ...

Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations This was a phase II multicenter trial in which refractory solid ...

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...

BOSTON--(BUSINESS WIRE)--Genialis, the RNA biomarker company, today announced an extension of its collaboration with Debiopharm, a Swiss-based global biopharmaceutical company, to develop a predictive ...

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery ...

Validation of a 15-Gene Prognostic Signature in Metastatic Clear Cell Renal Cell Carcinoma Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ...

“Taken together, CHEK2 expression has the potential to predict resistance or non-response to immunotherapy” In this paper, led by first author Helen Qian and corresponding author Crismita Dmello from ...

I've been lurking and dipping in and out of this thread, and have a scattered assortment of thoughts and somewhat-relevant expertise that I've finally decided to express in words. My bona fides: I've ...