Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal part of brain development.

Early in the progression of Alzheimer's and other neurodegenerative diseases, DNA inside neurons starts showing signs of ...

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

The class of drugs known as DNA Damage Response inhibitors, which work by blocking cancer cells’ ability to repair their own damaged DNA, is expanding rapidly beyond its original anchor, the PARP ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

Over the past decade, researchers at WashU Medicine have established that a molecule called SARM1 is a central trigger in the loss of axons, the vital wiring of the nervous system. Axon loss is ...

In most modern cells, DNA stores the genetic blueprint, and proteins replicate, repair and build from those blueprints. At ...

Accumulation of DNA damage in the brain's neurons may contribute to the development of Alzheimer's disease. New research in ...

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA ...