Repair of DNA double-strand breaks via homologous recombination can produce double Holliday junctions (dHJs) that require enzymatic separation. Topoisomerase IIIα (TopIIIα) together with RMI1 ...
A type of filamentous protein assembly known as agglomerates appear to offer advantages in intracellular engineering and synthetic biology and little to no deleterious effects on cellular fitness, ...
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