Modern therapeutics are shifting from their reliance on small molecules to biologics produced by cultured cells. The development and production of those biologics increasingly rely on computationally ...

Integrated analytical workflows are transforming cell line development by combining faster screening and streamlined decision-making.

Scientists have developed a way to engineer immune cells that specifically target tumors. The application of engineering cells first appeared in the 1980s, but the concept has significantly progressed ...

Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, ...

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have ...

Regenerative medicine combines tissue engineering and cell therapies to repair or replace damaged human tissues and organs. Key applications include treating osteoarthritis with mesenchymal stem cells ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

Although Chinese hamster ovary (CHO) cells have dominated therapeutic protein expression systems for decades, biomanufacturers still must deal with their inconsistent expression levels and varying ...