A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before ...

Nearly 150 years ago, scientists began to imagine how information might flow through the brain based on the shapes of neurons they had seen under the microscopes of the time. With today's imaging ...

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a single-step technique for ...

Expansion microscopy (ExM) is an attractive route to nanoscale imaging for labs without conventional super-resolution microscopes. It involves linking fluorescent markers through a gel infused into ...

A collection of protocols covering a variety of methods to achieve super resolution in microscopy to include structured illumination, single-molecule fluorescence and localization-based approaches.

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a ...

Expansion microscopy enhances conventional imaging by physically enlarging samples within a hydrogel matrix, surpassing diffraction limits. In this Primer, Vo et al. detail typical expansion ...

Expansion microscopy helped researchers visualize Plasmodium inside near-intact mosquitoes, preserving anatomical context for ...