A team of scientists from the Perelman School of Medicine at the University of Pennsylvania and Aum Biotech LLC have described the development of a novel cancer immunotherapy designed to target ...

Osaka, Japan – The immune system is tightly regulated to ensure that it only responds to actual health threats, instead of attacking our own bodies, which happens in cases of autoimmunity. Now, ...

Scientists at the Salk Institute say they have discovered that the Foxp3 protein is essential for creating the unique chromatin architecture of regulatory T cells and, in turn, promoting their immune ...

Understanding how regulatory T cells (Tregs) develop and work is key to determining how they might be manipulated to encourage the destruction of cancer cells or prevent autoimmunity. Cell behavior is ...

A potential new therapeutic option for the treatment of nonmuscle invasive bladder cancer: Combination of intravesical oncotherad immunotherapy and platelet rich plasma (PRP). This is an ASCO Meeting ...

Researchers determined the Foxp3 protein is actually a cofactor, hijacking DNA-binding proteins responding to the immunological environment of the T cell. Based on the type of response needed, ...

TBCRC009: A multicenter phase II study of cisplatin or carboplatin for metastatic triple-negative breast cancer and evaluation of p63/p73 as a biomarker of response. Background: Predictive markers of ...

Regulatory T cells are specialized immune cells that suppress the immune response and prevent the body from attacking its own cells. Understanding how these cells work is key to determining how they ...

Rosa Bacchetta is an associate professor of pediatrics at Stanford University. Her goal as a physician-scientist is to use modern technologies in the laboratory to find cures for untreatable pediatric ...