In a recent perspective published in the journal Cell Death and Differentiation, researchers in France, Germany, and Sweden discussed the unique mutational spectrum of the transformation-related ...
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
A new hypothesis article was published in Oncotarget (Volume 17) on January 3, 2026, titled “Hypothesis: HPV E6 and COVID ...
The tumor suppressor protein p53 plays a critical role in preventing cancer by regulating cell cycle, apoptosis, and genomic stability. However, mutations in the P53 gene are found in over 50% of ...
TP53 mutations are crucial in cancer development and treatment response, influenced by genetic and environmental factors. In CLL and AML, TP53 serves as a significant prognostic marker, affecting ...
The normal function of the p53 tumor suppressor protein is inactivated by different mutations in the TP53 gene in about half of all cancer cases, with Y220C being one the most frequent TP53 missense ...
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