Using a specific addition method to wet the powder bed in twin-screw granulation using a foam binder improves robustness for continuous solid-dosage drug product manufacturing. In less than a decade, ...

Granulation is a key step in solid dosage manufacturing and directly impacts product quality and process stability. However, the choice of wet granulation method is often driven by legacy decisions ...

The pharmaceutical manufacturing platforms of fluid-bed granulation and milling are widely used to modify particle size. However, the adoption of process analytical technology to monitor and control ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Pharmaceutical research and development (R&D) and industry require a continuous fluid-bed dryer that provides a lengthy process time and delivers a high standard for a long time. This article ...

Spatial filter techniques, along with delivering real-time particle size measurement, offer several further attractions such as simple hardware requirements, ease of use and reasonable commercial cost ...

Continuous granulation has emerged as a cornerstone of modern pharmaceutical manufacturing, transforming the traditional batch paradigm into an uninterrupted, end-to-end process. By integrating unit ...

Industrial engineer Kaan Ceylan argues that the U.S. must expand domestic and regional fertilizer production because repeated ...

Dry granulation, also called roller compaction, has been a popular method in recent years and has many applications. The powder is compressed between revolving rollers to generate flakes. The flakes ...