The internalization mechanisms associated with octaarginine and stearyl-octaarginine were investigated using confocal laser microscopy and flow cytometric analysis. Octaarginine is able to translocate ...

Antibody-Drug Conjugates (ADCs) are a fundamental technology in modern tumor-targeted therapy with their ‘tripartite integrated design’ of ‘precision carrier - stable linker - potent payload’: The ...

Purdue biochemistry professor W. Andy Tao's TITAN technology uses tiny dendrimers to illuminate complex cell processes. (Purdue Agricultural Communication/Tom Campbell) Download Photo WEST LAFAYETTE, ...

Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not ...

Tag-lite is a cellular screening platform from Cisbio Bioassays that enables the investigation of natural ligand, small molecule, or antibody binding to cell-surface proteins such as GPCRs and RTKs.

Meaningful Anticipated Reduction in Operating Expenses: In the aggregate, net of incremental operating costs and excluding any one-time charges associated with the internalization process, Granite ...