For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

– Atopic dermatitis and prurigo nodularis skin lesions show evidence of MRGPRX2 mast cell activation and activated macrophages – – AK006 inhibited mast cell activation and reduced mast cell numbers in ...

(BPT) – Do you often get a skin rash after you are exposed to an allergen or irritant? Do you also develop breathing problems and stomach issues? Bone or muscle pain? You may want to learn about mast ...

Advanced systemic mastocytosis (advSM) is a rare and serious form of systemic mastocytosis, a blood disorder that involves the overproduction of mast cells. Mast cells are a type of white blood cell ...

Why do we scratch? Scratching in response to itching is both pleasurable and harmful. In skin conditions, particularly dermatitis, scratching creates a vicious cycle, intensifying the itch and ...

Researchers at the University of Pittsburgh have uncovered new insights into the dual nature of scratching an itch, indicating that while it can worsen skin inflammation, it can also boost immune ...