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Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations, analysis suggests

Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited mutations in the BRCA1 or BRCA2 genes, according to the results of a matched ...
EurekAlert!

Integrative scATAC-seq and mtDNA mutation analysis reveals disease-driven regulatory aberrations in AML

Disruptions in transcriptional regulation during hematopoiesis can lead to abnormal hematopoietic differentiation and the development of leukemia. Understanding the underlying mechanisms of disease ...

BRAF gene mutation leads to different therapeutic responses in melanoma and colorectal cancer

A review article led by researchers from the B·ARGO group at the Germans Trias i Pujol Research Institute (IGTP) and from the Medical Oncology Department of the Catalan Institute of Oncology (ICO) in ...
ascopubs.org

Analysis of ATM germline mutations in solid tumors from Chinese patients.

Twenty-one gene recurrence scores in individuals with breast cancer associated with CHEK2 and ATM germline pathogenic variants. Characteristics and clinical outcome of BRCA germline mutation carriers ...
ScienceAlert on MSN

This rare genetic mutation kills brain cells, and we finally know why

Experiments on an ultra-rare genetic mutation that causes neurodegeneration in children have helped uncover a new mechanism ...
Oncology Nurse Advisor

Use of Tanning Beds More Than Doubles Melanoma Risk

Tanning bed usage was associated with an increased risk of melanoma, at an odds ratio of 2.85, while further analysis revealed a dose–response relationship between the number of tanning bed exposures ...