The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...

This Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing. The human genome is a vast landscape, with less than 2% of its sequence encoding proteins. For many years, ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...

Researchers have identified elusive DNA switches in brain support cells that influence genes tied to Alzheimer’s disease. When people think about DNA, they often picture genes that determine our ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are ...

SickKids researchers discovered that a long non-coding RNA, CISTR-ACT, directly regulates cell size. Using gene-editing tools ...

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases.

Originally classified as ‘junk DNA’, genomic regions which are transcribed into RNAs that do not serve as template for protein production have attracted increasing attention in the last two decades.

But only a tiny percentage of our DNA – around 2% – contains our 20,000-odd genes. The remaining 98% – long known as the non-coding genome, or so-called ‘junk’ DNA – includes many of the switches that ...