The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...
It's the San Francisco 49ers vs Indianapolis Colts on Monday Night Football in Week 16 of the 2025 NFL season. Here's how to ...
Stick with CNN Sports all afternoon and evening as we provide live updates and analysis from both games, starting with the 4:30 p.m. ET kick off of Rams-Panthers.
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