We report a new method to estimate the predictive performance of polygenic models for risk prediction and assess predictive performance for ten complex traits or common diseases. Using estimates of ...
Using polygenic risk scores along with positive family histories and breast cancer-associated gene mutations improves risk stratification for breast cancer screening. Compared with a lower polygenic ...
NEW ORLEANS — Causal artificial intelligence used to augment a polygenic risk score for CAD helped estimate how much individual patients must lower their LDL, systolic BP or both to overcome inherited ...
The potential of polygenic scores to improve risk stratification has reignited enthusiasm around the use of genetic information to help predict and prevent common disease. A new report from the PHG ...
In previous studies polygene mapping of a backcross population derived from haploid potato (Solanum tuberosum) and a diploid wild species (Solanum berthaultii) showed at least eight quantitative trait ...
Survey reveals nearly three-quarters of U.S. adults support using emerging technology to screen embryos during IVF for risk of developing certain health conditions or traits that arise from more than ...
Polygenic risk scores (PRS) combined with clinical factors improve POAG risk prediction, aiding in identifying high-risk patients. The study used OHTS data, showing low polygenic risk correlates with ...
Opinions differ as to the value of genetic information in the form of polygenic scores and the usefulness of polygenic score analysis as part of routine healthcare – clinical utility. Views on ...
Advances in genetics have made it possible to analyze thousands of genes at once, producing scores that estimate disease risk with high precision. But are polygenic risk scores ready to transform ...
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