A 50-year-old man presents with a 2-day history of fever, malaise, and erythematous skin with widespread pustules. He reports a history of psoriasis and is concerned about the recent development of ...

A 5-day-old female is transferred from another hospital due to irritability and a worsening pustular rash. The mother’s pregnancy, labor and delivery was complicated by a group B strep-positive ...

Recently, I had a patient with a germline loss-of-function mutation in the interleukin-36 receptor antagonist gene present to my clinic with a rapidly progressive generalized pustular psoriasis (GPP) ...

Please provide your email address to receive an email when new articles are posted on . A 3-year-old girl came running into her house, crying loudly with pain in her right hand. Her mother noticed ...

Treatment with the interleukin-36 inhibitor spesolimab was associated with improved lesion clearance vs placebo after one week, but also a greater incidence of infection and systemic drug reactions.

You’ve probably heard of psoriasis—the chronic inflammatory condition that can cause itchy, scaly patches on your skin. Less well-known is a rare form of the disease called pustular psoriasis, which ...

GPP can be triggered by the initiation and withdrawal of various medications, in particular the withdrawal of corticosteroids, and by infections, stress, and other conditions. 1,5,6,10 Patients with a ...

Acute generalized exanthematous pustulosis (AGEP) is a rare adverse skin reaction usually caused by medication or acute infection. As numerous diseases may present with pustular eruptions, it is ...

An international consensus statement on generalized pustular psoriasis (GPP) from the International Psoriasis Council (IPC) includes the recommendation that considerations such as body surface area ...