Dear Dr. Roach: I am a 74-year-old woman who is in good health. I was diagnosed with pyoderma gangrenosum on my left leg and I was in a lot of pain. Can you tell me the cause of this rare disease?

Pyoderma gangrenosum (PG) is a rare, noninfectious neutrophilic dermatosis. Clinically, it begins with sterile pustules that rapidly progress into painful ulcers of variable depth and size with ...

A 58-year-old woman presented to our emergency department with painful ulcers on the right side of her neck and on her left elbow. The ulcers, which had begun after minimal trauma, had increased in ...

Robert has to wrap his legs so tightly it feels "like an elastic band" ROBERT Lilley was diagnosed with a rare flesh-eating condition 12 years ago – and has lived in “unbearable pain” ever since. The ...

Please provide your email address to receive an email when new articles are posted on . A minimal important difference of 7-day pain scores was a 2-point improvement on an 11-point scale. A 2-point ...

Pyoderma gangrenosum was first described as an extraintestinal manifestation of inflammatory bowel disease (IBD) by Brunsting and colleagues in 1930. 1 They described painful enlarging necrotic ulcers ...

JENA, Germany, May 28, 2025 (GLOBE NEWSWIRE) -- InflaRx N.V. (Nasdaq: IFRX), a biopharmaceutical company pioneering anti-inflammatory therapeutics targeting the complement system, today announced that ...

It is thought to affect around one in 100,000 people in the UK and US. Pyoderma gangrenosum is believed to occur as a result of a pre-existing condition such as ulcerative colitis, Crohn's disease or ...

A 39-year-old woman with a history of regional enteritis presented with an itchy rash on a tattoo on her left leg that she had received two weeks earlier (Figure 1A). We diagnosed allergic contact ...

While the Phase 3 trial of vilobelimab in ulcerative pyoderma gangrenosum (PG) was terminated earlier this year due to futility regarding its prespecified primary endpoint (as previously disclosed), ...