Diversity, equity, and inclusion (DEI) champions: Lessons learned and implications for future programming to support cancer clinical trials. This is an ASCO Meeting Abstract from the 2023 ASCO Annual ...
Indications: Pyruvate dehydrogenase complex deficiency, typically associated with post-prandial lactic acidemia with a normal lactate/pyruvate ratio, can be assayed in freshly isolated blood ...
The specific activity of pyruvate carboxylase [pyruvate:carbon-dioxide ligase (ADP-forming); EC 6.4.1.1] in 3T3-L1 cells increases approximately 20-fold when these cells differentiate to an ...
Glycolysis is the breakdown of glucose into two pyruvate molecules. This process does not require oxygen (it is anaerobic). The production of pyruvate from glucose involves the production of several ...
During an epileptic seizure, pyruvate levels in astrocytes increased, while ATP levels in neurons decreased. The experiments suggest that the transfer of metabolic energy molecule transfer may be ...
Proliferating cells, in particular tumor cells, express a dimeric isoenzyme of pyruvate kinase, termed Tumor M2 pyruvate kinase. In the last few years, much attention has been paid to this novel tumor ...
Acetolactate synthase, also known as acetohydroxyacid synthase (AHAS), is an enzyme involved in the branched chain amino acid biosynthesis pathway. AHAS is a thiamine diphosphate (ThDP)-dependent ...