Imsidolimab is a humanized IgG4 antibody that inhibits the function of the interleukin-36-receptor. Treatment with imsidolimab led to significant clearance of pustulation, erythema, and scaling in ...

Mark G. Lebwohl, MD, discusses how IL-36 mutations can play a part in disease presentation and how IL-17 and IL-23 pathways are more often implicated in plaque psoriasis. Aaron Farberg, MD, and Maria ...

Please provide your email address to receive an email when new articles are posted on . The mean annualized flare rate per patient per year was 0.91, with a mean time of 5.9 months between flares.

Spevigo is a humanized monoclonal immunoglobulin G1 antibody that inhibits interleukin-36 signaling. The Food and Drug Administration (FDA) has approved Spevigo ® (spesolimab-sbzo) for the treatment ...

The FDA has approved the monoclonal antibody spesolimab (Spevigo) as the first treatment for generalized pustular psoriasis (GPP), Boehringer Ingelheim announced. The approval stipulates use of the ...

Generalized pustular psoriasis may be caused or triggered by various factors, including genetic mutations, infections, and certain medications. Generalized pustular psoriasis (GPP) is a severe form of ...

Many patients with generalized pustular psoriasis (GPP) flares got no specific treatment for them, despite their high risk of severe complications, according to the biggest study of these episodes to ...

INGELHEIM, Germany--(BUSINESS WIRE)--Today, at the 25 th World Congress of Dermatology (WCD), Boehringer Ingelheim presented new late-breaking data from the EFFISAYIL™ 2 trial showing that spesolimab ...

Ryan Haumschild, PharmD, MS, MBA: Welcome to this AJMC ® [The American Journal of Managed Care ®] program titled, “Generalized Pustular Psoriasis: Provider and Payer Considerations for Care.” I am Dr ...

Scalp folliculitis is a skin condition that occurs when the hair follicles on the scalp become inflamed. This results in pustules, whiteheads, or other pimple-like bumps on the scalp that can be ...

Erosive pustular dermatosis (EPD) is a chronic inflammatory skin disorder predominantly affecting the scalp of older individuals, often in areas of pre-existing actinic damage and androgenetic ...

Scalp folliculitis is a skin condition that occurs when the hair follicles on the scalp become inflamed. This results in pustules, whiteheads, or other pimple-like bumps on the scalp that can be ...