Understanding gene expression in different cell types within their spatial context is a key goal in genomics research. SPADE (SPAtial DEconvolution), our proposed method, addresses this by integrating ...

The spatial organization of cells is fundamental to multicellular life as it influences development, function and evolution. During development, the precise spatial arrangement of cells ensures proper ...

Over the past decade, the Human Cell Atlas community has accomplished something that will define a generation of biology.

A comprehensive map has been built of cell types in a mammalian brain using spatial and single-cell genomics. The atlas delineates several thousand cell populations across the entire mouse brain, ...