THIN-LAYER CHROMATOGRAPHY (TLC) has long been a staple of the organic laboratory, and its silica-on-glass plates are familiar even to undergraduate chemistry majors. But for advanced applications, TLC ...

The search for drugs to treat and prevent COVID-19, has led to the repurposing of available small-molecule pharmaceuticals such as remdesivir, and the development of several new drugs and vaccines. 1 ...

Users often feel a sense of accomplishment when achieving well-defined, isolated spots with a thin-layer chromatography (TLC) plate. Users set up a flash chromatography method, prepare the column, ...

Join host Neil Lander as he welcomes Katy Rhynard, Associate Director of Laboratory Informatics at Gilead Sciences. In this episode, Katy discusses the intricacies of validating chromatographic ...

A new method allows chemists to measure how fast a small molecule binds to and unbinds from a protein without modifying or labeling either molecule (Anal. Chem. 2014, DOI: 10.1021/ac503391c).