A new lipid nanoparticle platform delivers full-length antibodies inside cells, unlocking intracellular targets in cancer, ...

A team led by researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute has discovered a promising new approach to treating advanced colorectal cancer. The study, ...

Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two ...

Potent drugs like chemotherapy can be life-saving, but often with life-threatening side effects. Notably, they can be indiscriminate, killing both cancer cells and healthy cells in one swoop.

MIT and Harvard scientists have designed an advanced type of immune cell called a CAR-NK cell that can destroy cancer while avoiding attack from the body’s own immune defenses. This innovation could ...

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while ...

There is a constant war going on in your body. Working against you are viruses and cancer cells growing uncontrollably, threatening your tissues and organs. Fighting on your side are immune cells such ...

A first-in-class nanoparticle injection sneaks antibodies into pancreatic cancer cells to clear mutant KRAS, shrinking tumors in mice while sparing healthy tissue.