In this presentation we presented an innovative integrated system designed to automate the tangential flow filtration (TFF) process based on inline concentration measurement. This system employs ...

Real-time and in-line accurate measuring of protein (monoclonal antibody, or mAb) concentration has been shown across a wide dynamic range (0–135 g/L) through the ...

The results found that repeatability testing found all 15 processes to be with in specification for target final concentration. After using a process analytical technology (PAT)-automated tangential ...

Monoclonal antibody (mAb) manufacturers struggling with single-use technology (SUT)-derived impurities should use ultrafiltration and diafiltration as the basis of their removal strategies, according ...

Monoclonal antibody (mAb) development is increasingly moving toward high-concentration formulations to support subcutaneous delivery, improve patient convenience, and enable next-generation ...