In mammalian cells, the nucleolus is the central site for ribosome biogenesis. It is composed of distinct subcompartments: the fibrillar center (FC), the dense fibrillar component (DFC), the periphery ...

This is a preview. Log in through your library . Abstract To understand how nuclear machineries are targeted to accurate locations during nuclear assembly, we investigated the pathway of the ribosomal ...

The objective of this study was to utilize sub-nucleolar fractionation to elucidate the role of PHF6 in regulating rDNA expression. We observed nucleolar PHF6 to be localized within both the FC and ...

This is a preview. Log in through your library . Abstract The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in ...