This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Scaling up single-cell sequencing studies allows scientists to uncover rare cell types, better understand disease states, and track cellular changes over time. However, processing, assaying, and ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...

Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Kimchi may do far more than add flavor to meals—it could help fine-tune the human immune system. A clinical study using ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

The field of immunogerontology investigates age-associated declines in immune function, particularly focusing on the reduced lymphoid potential of ...